Quantum Chemistry of the Color Tuning Mechanism in the Photobiological System

• Hasegawa Jun-ya

  Department of Synthetic Chemistry and Biological Chemistry, Faculty of Engineering, Kyoto University

Bibliographic Information

Other Title

• 光機能性蛋白質におけるカラー・チューニングの量子化学

Abstract

In visual systems and fluorescent proteins, controlling the photo-absorption/emission energy (color tuning) of the chromophore is the essentials to furnish a protein with the photo-functionality. Depending on the protein environment, the chromophores show a variety of colors, which are relevant to the character of the excited states and to the interactions between the chromophore and the environment. Here we summarize our recent studies on the spectral tuning mechanism of the human visual cone pigments and the fluorescent proteins. These studies elucidated a common feature in the color tuning, which also suggests a strategy to artificially control the color of proteins. We also explain our recent progress in developing the symmetry-adapted cluster-configuration interaction (SAC-CI) method and hybrid quantum mechanical/molecular mechanical (QM/MM) method particularly for studying the photo-functional proteins.

Journal

• Molecular Science

  Molecular Science 4 (1), A0031-, 2010

  Japan Society for Molecular Science

Keywords

• human visual cone pigment
• firefly luciferase
• fluorescent protein
• QM/MM
• SAC-CI method

Details

• CRID: 1390282680258506752
• NII Article ID: 130000339436
• DOI: 10.3175/molsci.4.a0031
• ISSN: 18818404
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed