Rhodium-Catalyzed Organothio Exchange Reaction of .ALPHA.-Organothioketones with Disulfides

• Arisawa Mieko

  Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University

• Toriyama Fumihiko

  Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University

• Yamaguchi Masahiko

  Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University WPI Research Center, Advanced Institute for Materials Research, Tohoku University

Bibliographic Information

Other Title

• Rhodium-catalyzed organothio exchange reaction of α-organothioketones with disulfides
• Rhodium catalyzed organothio exchange reaction of a organothioketones with disulfides

Abstract

RhH(PPh₃)₄ and 1,2-bis(diphenylphosphino)ethane (dppe) catalyzed the organothio exchange reaction of α-organothioketones and organic disulfides. The reaction was affected by the structure of the substrate: α-phenylthio and α-alkylthio aryl ketones reacted effectively with diaryl and dialkyl disulfides; α-phenylthio dialkyl ketones reacted with diaryl disulfides but not with dialkyl disulfides; diaryl disulfides with electron-donating p-substituents were more reactive than those with electron-withdrawing p-substituents.

Journal

• Chemical and Pharmaceutical Bulletin

  Chemical and Pharmaceutical Bulletin 58 (10), 1349-1352, 2010

  The Pharmaceutical Society of Japan

Keywords

• rhodium catalyst
• organothio exchange reaction
• thioketone
• disulfide

Details

• CRID: 1390001204173027968
• NII Article ID: 130000405639
• NII Book ID: AA00602100
• DOI: 10.1248/cpb.58.1349
• ISSN: 13475223
• ISSN: 00092363
• NDL BIB ID: 10825214
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10825214
• Web Site: http://www.jstage.jst.go.jp/article/cpb/58/10/58_10_1349/_pdf
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed