Importance of Controlling Drug-resistant Pseudomonas aeruginosa Infection: Experience from Lung Transplantation in a Cystic Fibrosis Case

• Yamamoto Yoshihiro

  Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences

• Izumikawa Koichi

  Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences

• Hara Atsuko

  Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences

• Fujita Hanako

  Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences

• Amenomori Misato

  Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences

• Sakamoto Noriho

  Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences

• Seki Masafumi

  Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences

• Kakeya Hiroshi

  Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences

• Yanagihara Katsunori

  Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences

• Takasaki Kenji

  Department of Otolaryngology-Head and Neck Surgery, Nagasaki University Graduate School of Biomedical Sciences

• Miyazaki Takuro

  Division of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences

• Tsuchiya Tomoshi

  Division of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences

• Yamasaki Naoya

  Division of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences

• Tagawa Tsutomu

  Division of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences

• Nagayasu Takeshi

  Division of Surgical Oncology, Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences

• Kohno Shigeru

  Department of Molecular Microbiology and Immunology, Nagasaki University Graduate School of Biomedical Sciences

Abstract

Cystic fibrosis (CF) is rare in Japan. We encountered a CF case with drug-resistant Pseudomonas aeruginosa infection and successfully performed lung transplant from living related donors. A combination of beta-lactams and aminoglycosides for drug-resistant P. aeruginosa infection was administered before lung transplantation. Intravenous colistin was also used immediately before and after transplant surgery. Gram staining of respiratory specimens was performed every day after surgery and it was useful in monitoring infection status. Strict monitoring of infections by the Gram staining and culture of respiratory specimens is considered to be effective in preventing lower respiratory infection in lung transplantation.<br>

Journal

• Internal Medicine

  Internal Medicine 49 (21), 2353-2358, 2010

  The Japanese Society of Internal Medicine

Keywords

• cystic fibrosis
• <i>Pseudomonas aeruginosa</i>
• lung transplantation
• ventilator-associated tracheobronchitis

Details

• CRID: 1390282679847086336
• NII Article ID: 130000413356
• NII Book ID: AA10827774
• DOI: 10.2169/internalmedicine.49.3932
• ISSN: 13497235
• ISSN: 09182918
• HANDLE: 10069/24562
• Web Site: https://nagasaki-u.repo.nii.ac.jp/records/14567
• Web Site: http://www.jstage.jst.go.jp/article/internalmedicine/49/21/49_21_2353/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2011206444
• Text Lang: en
• Data Source:
  • JaLC
  • IRDB
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed