Upper Lobe-Dominant Pulmonary Fibrosis Showing Deposits of Hard Metal Component in the Fibrotic Lesions

DOI Web Site 被引用文献3件 参考文献4件
  • Kaneko Yoshiko
    Department of Respiratory Medicine, University of Tsukuba
  • Kikuchi Norihiro
    Department of Respiratory Medicine, University of Tsukuba
  • Ishii Yukio
    Department of Respiratory Medicine, University of Tsukuba
  • Kawabata Yoshinori
    Department of Pathology, Saitama Cardiovascular and Respiratory Center
  • Moriyama Hiroshi
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Terada Masaki
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Suzuki Eiichi
    Department of General Medicine, Niigata University Medical and Dental Hospital
  • Kobayashi Masayoshi
    EPMA Laboratory, Center of Instrumental Analysis, Niigata University
  • Watanabe Kouichi
    EPMA Laboratory, Center of Instrumental Analysis, Niigata University
  • Hizawa Nobuyuki
    Department of Respiratory Medicine, University of Tsukuba

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抄録

We present a 54-year-old man employed in the field of hard metal manufacturing who complained of progressive dyspnea and weight loss. His chest radiograph showed bilateral fibrosis predominantly distributed in the upper lobes with bilateral pleural effusions, and a strong reduction in lung volume. Lung histopathology showed apical cap-like fibrosis but no giant cell interstitial pneumonia. Electron probe microanalysis detected tungsten deposits in the fibrotic region: we therefore considered this to be a case of hard metal disease. Hard metal disease should be considered as one possibility in the differential diagnosis of upper lobe-dominant pulmonary fibrosis.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 49 (19), 2143-2145, 2010

    一般社団法人 日本内科学会

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