Arteriosclerosis risk and body fat distribution in obese children with metabolic syndrome
-
- Oguri Kazuo
- Shizuoka Sangyo University
-
- Hoshikawa Yoshihiro
- Sports Photonics Laboratory, Hamamatsu Photonics K. K.
-
- Togashi Kenji
- Faculty of Education, Mie University
-
- Kasuga Kosho
- Faculty of Education, Gifu University
-
- Tachi Toshiki
- Shizuoka Sangyo University
-
- Fujii Katsunori
- Aichi Institute of Technology
-
- Matsuoka Toshio
- Department of Sports Medicine and Sports Science, Gifu University Graduate school of Medicine
Bibliographic Information
- Other Title
-
- メタボリックシンドロームを合併した肥満小児における動脈硬化の危険性と体脂肪分布
- メタボリックシンドローム オ ガッペイ シタ ヒマン ショウニ ニ オケル ドウミャク コウカ ノ キケンセイ ト タイシボウ ブンプ
Search this article
Abstract
The scarcity of published data regarding whether metabolic syndrome (MS) is involved in development of arteriosclerosis in children led us conduct the present study. To examine the relationship between MS and early arteriosclerosis risk in childhood, we compared percent body fat (%BF), visceral fat area (VFA), small dense low-density lipoprotein (LDL) particle size and high sensitivity C-reactive protein (hsCRP) among obese children with MS, obese and non-obese children without MS. The subjects were 76 Japanese children (41 obese, 35 non-obese) aged 7.0-12.6 years. Obesity was determined upon an obesity index of more than+20%. Obese children were grouped into with (n=5) and without (n=30) MS (abdominal obesity plus at least two other factors from hypertriglyceridemia, low high-density lipoprotein-cholesterol, hypertension, and high fasting glucose). Obese children with MS had significantly higher %BF, as evaluated with air-displacement plethysmography, and VFA, as determined by magnetic resonance imaging, than obese and non-obese children without MS (p<0.05). VFA was strongly associated with %BF (r=0.709, p<0.05) and obesity index (r=0.742, p<0.05). Obese children with MS had significantly smaller LDL size and higher hsCRP, which is known to be novel markers characterizing the atherosclerotic process at an early stage, than other groups. Our findings suggest that metabolic syndrome more than obesity per se may have large total and visceral fat mass, and be involved in early arteriosclerosis risk in children.
Journal
-
- Japan Journal of Human Growth and Development Research
-
Japan Journal of Human Growth and Development Research 2010 (46), 46_1-46_10, 2010
Japan Society of Human Growth and Development
- Tweet
Details 詳細情報について
-
- CRID
- 1390001205282786048
-
- NII Article ID
- 130000414714
-
- NII Book ID
- AA11280061
-
- ISSN
- 1884359X
- 13408682
-
- NDL BIB ID
- 10628729
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
-
- Abstract License Flag
- Disallowed