Ganglioneuroma in the Urinary Bladder of a Dog

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  • SAKAI Hiroki
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University
  • YONEMARU Kayoko
    Gifu Pathology Laboratory
  • TAKEDA Masaaki
    Emi Animal Hospital
  • NIIMI Kenta
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University
  • MURAKAMI Mami
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University
  • HIRATA Akihiro
    Division of Animal Experiment, Life Science Research Center, Gifu University
  • YANAI Tokuma
    Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University

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  • Pathology: Ganglioneuroma in the urinary bladder of a dog

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Abstract

An 11-year-old male Labrador retriever presented with chronic oliguria. Ultrasonography findings revealed a protruding mass at the neck of the urinary bladder. A cystotomy was performed, and the mass was removed by ligation with surgical sutures. Histopathological examination revealed conspicuous foci with a variable number of ganglion cells in the tumor and abundant interwoven bundles of schwannian cells with fine fibers. The ganglion cells were positive for neuron-specific enolase and neurofilament. The schwannian cells were positive for vimentin, S-100 protein, and glial fibrillary acidic protein. Thus, according to the classification of tumor with neuronal cell differentiation, the urinary tumor was diagnosed as a ganglioneuroma.<br>

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