IgG4-Related Pleural Disease Diagnosed by a Re-Evaluation of Chronic Bilateral Pleuritis in a Patient Who Experienced Occasional Acute Left Bacterial Pleuritis

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著者

    • Yamamoto Hiroshi
    • The First Department of Internal Medicine, Shinshu University School of Medicine, Japan
    • Koizumi Tomonobu
    • The First Department of Internal Medicine, Shinshu University School of Medicine, Japan
    • Uehara Takeshi
    • Department of Pathology, Shinshu University School of Medicine, Japan
    • Hamano Hideaki
    • The Second Department of Internal Medicine, Shinshu University School of Medicine, Japan
    • Kawa Shigeyuki
    • Center for Health, Safety and Environmental Management, Shinshu University School of Medicine, Japan
    • Kubo Keishi
    • The First Department of Internal Medicine, Shinshu University School of Medicine, Japan
    • Suzuki Toshiro
    • The First Department of Internal Medicine, Shinshu University School of Medicine, Japan
    • Yasuo Masanori
    • The First Department of Internal Medicine, Shinshu University School of Medicine, Japan
    • Kobayashi Orie
    • The First Department of Internal Medicine, Shinshu University School of Medicine, Japan
    • Tsushima Kenji
    • The First Department of Internal Medicine, Shinshu University School of Medicine, Japan
    • Ito Michiko
    • The First Department of Internal Medicine, Shinshu University School of Medicine, Japan
    • Urushihata Kazuhisa
    • The First Department of Internal Medicine, Shinshu University School of Medicine, Japan
    • Yamazaki Yoshitaka
    • The First Department of Internal Medicine, Shinshu University School of Medicine, Japan
    • Hanaoka Masayuki
    • The First Department of Internal Medicine, Shinshu University School of Medicine, Japan

抄録

A 78-year-old man with cryptogenic chronic bilateral lymphoplasmacytic pleuritis, diagnosed based on left parietal pleural biopsy specimens obtained by pleuroscopy, developed acute left bacterial pleuritis. The left pleural effusion was neutrophil dominant, however, the right pleural effusion showed lymphoplasmacytic infiltration. Laboratory examinations revealed that his serum IgG4 concentration was increased, with a higher level of IgG4 in the right pleural effusion. Re-evaluation of the previous biopsy specimens using an immunostaining method revealed numerous IgG4-positive plasma cell infiltrations with IgG4-positive/IgG-positive plasma cells at 85.4%. Accordingly, the new diagnosis of this patient was considered to be chronic bilateral IgG4-related pleuritis.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 50(8), 893-897, 2011

    一般社団法人 日本内科学会

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