Diffuse Large B-Cell Lymphoma Carrying both t(3 ; 7)(q27 ; p12) and t(8 ; 14)(q24 ; q32)

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  • Katsura Yukitaka
    Department of Hematology, Mito Medical Center, National Hospital Organization, Japan
  • Ohta Ikuyo
    Department of Hematology, Mito Medical Center, National Hospital Organization, Japan
  • Yoshida Chikashi
    Department of Hematology, Mito Medical Center, National Hospital Organization, Japan
  • Ohtani Haruo
    Department of Pathology, Mito Medical Center, National Hospital Organization, Japan
  • Komeno Takuya
    Department of Hematology, Mito Medical Center, National Hospital Organization, Japan

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抄録

We report a 60-year-old man with diffuse large B-cell lymphoma harboring both t(3 ; 7)(q27 ; p12) and t(8 ; 14)(q24 ; q32). Although he received six courses of conventional combination chemotherapy plus rituximab, early relapse occurred. Four courses of an intensive salvage regimen and high-dose chemotherapy with autologous peripheral blood stem cell transplantation were performed. The patient has remained in complete remission for over 24 months. This case is noteworthy because both genetic abnormalities are implicated in lymphomagenesis.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 50 (8), 905-908, 2011

    一般社団法人 日本内科学会

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