Prognostic Significance of Right Ventricular Dimension on Acute Decompensation in Chronic Left-Sided Heart Failure

• Maekawa Emi

  Department of Cardio-Angiology, Kitasato University School of Medicine

• Inomata Takayuki

  Department of Cardio-Angiology, Kitasato University School of Medicine

• Watanabe Ichiro

  Department of Cardio-Angiology, Kitasato University School of Medicine

• Yanagisawa Tomoyoshi

  Department of Cardio-Angiology, Kitasato University School of Medicine

• Mizutani Tomohiro

  Department of Cardio-Angiology, Kitasato University School of Medicine

• Shinagawa Hisahito

  Department of Cardio-Angiology, Kitasato University School of Medicine

• Koitabashi Toshimi

  Department of Cardio-Angiology, Kitasato University School of Medicine

• Takeuchi Ichiro

  Department of Cardio-Angiology, Kitasato University School of Medicine

• Tokita Naoki

  Department of Diagnostic Radiology, Kitasato University School of Medicine

• Inoue Yusuke

  Department of Diagnostic Radiology, Kitasato University School of Medicine

• Izumi Tohru

  Department of Cardio-Angiology, Kitasato University School of Medicine

抄録

Right ventricular (RV) dysfunction has been discussed in relation to an adverse outcome in heart failure (HF). The aim of this study was to analyze the relationship between RV function with HF exacerbation and its subsequent long-term outcome in patients with chronic left-sided HF.<br>We studied 122 consecutive patients who were admitted for dyspnea due to exacerbated left-sided HF with a left ventricular (LV) ejection fraction of less than 40%. Conventional echocardiography was performed in the study subjects on admission and at discharge. Cox proportional hazards analysis revealed that RV end-diastolic dimension (RVDd) (hazard ratio 1.131, P = 0.005, 95% confidence interval 1.039-1.231) and the serum level of creatinine on admission were independent predictors of subsequent cardiac-related death, but RVDd at discharge and other LV parameters were not. Thus, patients were divided into tertiles on the basis of RVDd on admission: < 32 mm (n = 37), 32-40 mm (n = 43), and ≥ 40 mm (n = 42). According to the increase in the RVDd category, the cardiac-related death-free rate significantly decreased. Among the 3 groups, the pulse pressure and serum total bilirubin levels that demonstrated low cardiac output syndrome (LOS) parameters had significant differences.<br>RVDd on admission could be measured noninvasively and easily to predict a worse long-term prognosis of chronic left-sided HF on admission, and showed correlations with LOS parameters.

収録刊行物

• International Heart Journal

  International Heart Journal 52 (2), 119-126, 2011

  一般社団法人 インターナショナル・ハート・ジャーナル刊行会

キーワード

• Right ventricular dimension
• Heart failure
• Acute exacerbation
• Prognosis
• Low cardiac output

詳細情報

• CRID: 1390001205225469440
• NII論文ID: 130000653068
• DOI: 10.1536/ihj.52.119
• ISSN: 13493299
• ISSN: 13492365
• Web Site: https://www.jstage.jst.go.jp/article/ihj/52/2/52_2_119/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2012069317
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可