チャーガ(カバノアナタケ)のマウス皮膚二段階発癌実験の腫瘍抑制効果 Inhibitory Effect of Chaga (Inonotus obliquus) on Tumor Promotion in Two-Stage Mouse Skin Carcinogenesis

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Author(s)

Abstract

チャーガ(<i>Inonotus obliquus</i> の菌核)は,ロシア,ポーランド,バルト海の数ヵ国で癌,心血管疾患,糖尿病の治療に民間療法として広く使われてきた.本研究では,チャーガの内服が,7,12-dimethylbenz[<i>a</i>]anthracene でイニシエーションをし 12-<i>O</i>-tetradecanoylphorbol-13-acetate でプロモートするマウス皮膚二段階発癌を抑制することが明らかになった.<br>

Chaga (the sclerotia of <i>Inonotus obliquus</i>) has been widely used as a folk medicine in the treatment of cancer, cardiovascular disease and diabetes in Russia, Poland, and several Baltic countries. More recently, this herb has been assessed for its cancer-preventing activity. Using a mouse model of skin cancer, oral administration of Chaga was found to inhibit tumor promotion by 12-<i>O</i>-tetradecanoylphorbol-13-acetate following initiation with 7,12-dimethylbenz[<i>a</i>]anthracene in mouse skin.<br>

Journal

  • Japanese Journal of Complementary and Alternative Medicine

    Japanese Journal of Complementary and Alternative Medicine 8(1), 29-32, 2011

    The Japanese Society for Complementary and Alternative Medicine

Codes

  • NII Article ID (NAID)
    130000654940
  • NII NACSIS-CAT ID (NCID)
    AA12095429
  • Text Lang
    ENG
  • ISSN
    1348-7922
  • NDL Article ID
    11086339
  • NDL Source Classification
    ZS47(科学技術--医学--治療医学・看護学・漢方医学)
  • NDL Call No.
    Z74-E199
  • Data Source
    NDL  J-STAGE 
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