Primary Bilateral Adrenal Intravascular Large B-cell Lymphoma Associated with Adrenal Failure

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  • FUKUSHIMA Ayumi
    The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine
  • OKADA Yosuke
    The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine
  • TANIKAWA Takahisa
    The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine
  • ONAKA Takashi
    The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine
  • TANAKA Aya
    The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine
  • HlGASHI Takehiro
    The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine
  • TSUKADA Junichi
    The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine
  • TANAKA Yoshiya
    The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, School of Medicine

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We report a rare case of bilateral primary adrenal non-Hodgkin's lymphoma with adrenal failure. A 66-year-old woman developed symptoms of adrenal failure. The cause of adrenal failure was suspected to be malignant lymphoma based on the high levels of serum soluble interleukin-2 receptor and LDH. Bilateral adrenalectomy was performed and pathological examination showed intravascular large B-cell lymphoma (IVL). Although complete remission was achieved, recurrence occurred three months later with brain metastases. IVL should be suspected in patients with bilateral adrenal tumors who present with rapidly progressive adrenal failure.<br>(Internal Medicine 42: 609-614, 2003)

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  • Internal Medicine

    Internal Medicine 42 (7), 609-614, 2003

    一般社団法人 日本内科学会

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