Hypertension and Genes.

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  • HIGAKI Jitsuo
    The Department of Geriatric Medicine, Osaka University Medical School
  • KATSUYA Tomohiro
    The Department of Geriatric Medicine, Osaka University Medical School
  • MORISHITA Ryuichi
    The Department of Geriatric Medicine, Osaka University Medical School
  • OGIHARA Toshio
    The Department of Geriatric Medicine, Osaka University Medical School

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抄録

Under classical strategy, scientists have tried first to find a physiological phenomenon specific for essential hypertension, then to identify the protein underlying the physiological abnormality, and finally to clarify the causative gene which encoded the protein. On the other hand, under the reverse genetic approach, the correlation between hypertension and genetic abnormality is identified first, and then the pathogenesis is clarified-in reverse order. Therefore, it is not extraordinary for unexpected results to be obtained in the correlation between a gene and a disease, suggesting that this approach has a possibility to be a breakthrough in the chaos of hypertension research.

収録刊行物

  • Internal Medicine

    Internal Medicine 40 (2), 144-147, 2001

    一般社団法人 日本内科学会

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