Acquired Idiopathic Pure Red Cell Aplasia in a Hemodialyzed Patient with Inactive Systemic Lupus Erythematosus.

  • OKADA Hirokazu
    The Department of Internal Medicine, Keio University School of Medicine
  • SUZUKI Hiromichi
    The Department of Internal Medicine, Keio University School of Medicine
  • UCHIDA Hideo
    The Department of Internal Medicine, Keio University School of Medicine
  • KANNO Yoshihiko
    The Department of Internal Medicine, Keio University School of Medicine
  • KITAMURA Yuko
    The Department of Internal Medicine, Keio University School of Medicine
  • HISAMATSU Tadakazu
    The Department of Internal Medicine, Keio University School of Medicine
  • DEGUCHI Nobuhiro
    Central Dialysis Unit, Keio University School of Medicine
  • HAYASHI Daisuke
    Division of Dialysis, Shimada General Hospital
  • SARUTA Takao
    The Department of Internal Medicine, Keio University School of Medicine

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抄録

A male patient suffered chronic renal failure due to lupus nephritis and was undergoing hemodialysis. Six years after beginning hemodialysis, anemia developed, which improved by erythropoietin. Unresponsiveness to erythropoietin gradually appeared, and with a suspicion of pure red cell aplasia, he was treated with a high-dose corticosteroid but the unresponsiveness did not improve. Neither his serum nor lymphocytes inhibited erythropoiesis of either normal bone marrow stem cells or his own in vitro. These observations suggest an impaired hematopoietic microenvironment in his bone marrow.<br>(Internal Medicine 33: 492-495, 1994)

収録刊行物

  • Internal Medicine

    Internal Medicine 33 (8), 492-495, 1994

    一般社団法人 日本内科学会

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