-
- Shibuya Kazumoto
- Department of Neurology, Graduate School of Medicine, Chiba University, Japan
-
- Misawa Sonoko
- Department of Neurology, Graduate School of Medicine, Chiba University, Japan
-
- Horikoshi Takuro
- Department of Radiology, Graduate School of Medicine, Chiba University, Japan
-
- Kanai Kazuaki
- Department of Neurology, Graduate School of Medicine, Chiba University, Japan
-
- Isose Sagiri
- Department of Neurology, Graduate School of Medicine, Chiba University, Japan
-
- Nasu Saiko
- Department of Neurology, Graduate School of Medicine, Chiba University, Japan
-
- Sekiguchi Yukari
- Department of Neurology, Graduate School of Medicine, Chiba University, Japan
-
- Noto Yu-ichi
- Department of Neurology, Graduate School of Medicine, Chiba University, Japan
-
- Fujimaki Yumi
- Department of Neurology, Graduate School of Medicine, Chiba University, Japan
-
- Nakaseko Chiaki
- Division of Hematology, Department of Clinical Cell Biology, Chiba University Hospital, Japan
-
- Kuwabara Satoshi
- Department of Neurology, Graduate School of Medicine, Chiba University, Japan
この論文をさがす
抄録
Objective To study the utility of CT for detection of small bone lesions in POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome. For patients with a solitary bone lesion, irradiation is a first-line treatment, whereas systemic chemotherapy is indicated for patients with multiple bone lesions. Therefore it is important to correctly identify the number of bone lesions.<br> Methods We studied the sensitivity of chest/abdomen/pelvic CT to detect bone lesions in 28 patients with POEMS syndrome. 99mTc-HMDP bone scintigraphy was performed in 14 patients, and the results were compared with CT.<br> Results CT showed multiple bone lesions in 68% of the 28 patients, and 71% of the lesions had a diameter <10 mm. In 14 patients who underwent both CT and scintigraphy, bone lesions were detected in 57% by CT and in 79% by scintigraphy, but the location and nature of the identified lesions were considerably different; CT frequently showed small lesions (diameter <10 mm) in the vertebrae and pelvis, which were not detected by scintigraphy, whereas scintigraphy could show lesions in the skull and long bones. Overall, by using both examinations, multiple bone lesions were found for 86% of patients.<br> Conclusion CT is particularly useful to detect small bone lesions. CT and bone scintigraphy are complementary, and therefore both should be performed for bone survey in POEMS syndrome.<br>
収録刊行物
-
- Internal Medicine
-
Internal Medicine 50 (13), 1393-1396, 2011
一般社団法人 日本内科学会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390282679847769856
-
- NII論文ID
- 130000770514
-
- ISSN
- 13497235
- 09182918
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可