Adult Still's Disease with Sjoegren's Syndrome Successfully Treated with Intravenous Pulse Methylprednisolone and Oral Cyclophosphamide.

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  • SATO Masaki
    the Division of Clinical Immunology, Department of Medicine, Jichi Medical School
  • TAKEDA Akira
    the Division of Clinical Immunology, Department of Medicine, Jichi Medical School
  • HONZU Hiromi
    Department of Internal Medicine, Saiseikai Utsunomiya Hospital
  • SAKU Naohiko
    Pulmonary Medicine, Department of Medicine, Jichi Medical School
  • MINATO Nagahiro
    Department of Immunology and Cell Biology, Faculty of Medicine, Kyoto University
  • KANO Shogo
    the Division of Clinical Immunology, Department of Medicine, Jichi Medical School

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Abstract

A patient with adult Still's disease and Sjögren's syndrome failed to respond to conventional doses of corticosteroids. Therefore intravenous pulse methylprednisolone combined with oral cyclophosphamide was given which subsequently resolved the flare of rashes, fevers, and arthritis. This combination therapy may be a useful therapy to consider in patients with adult Still's disease who are resistant to conventional treatment and may allow a reduction in daily corticosteroid requirement.<br>(Internal Medicine 32: 730-732, 1993)

Journal

  • Internal Medicine

    Internal Medicine 32 (9), 730-732, 1993

    The Japanese Society of Internal Medicine

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