魚類の補体の代替経路による殺菌作用  [in Japanese] Bactericidal Reaction by the Alternative Pathway of Fish Complement  [in Japanese]

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Abstract

1. ウナギ,ニジマス,コイ,ティラピア,クロダイの新鮮血清の殺菌作用について,E. coliを用いて調べた。2. すべての魚種の新鮮血清に殺菌作用が認められ,ザイモサン処理,EDTA, EGTA添加が殺菌作用に及ぼす影響により,この殺菌作用は補体の代替経路によるものと判断された。3. しかし,各種処理が及ぼす影響に違いがみられ,魚種により代替経路活性過程が一様でないことが示唆された。4. 魚病細菌V.anguillarum, E. tardaに対する殺菌作用も調べたが,E. coliに対する結果よりもその程度は低かった。

The bactericidal activity of normal sera from five species of fish, eel, rainbow trout, carp, tilapia and black sea bream, was investigated.<BR>All sera examined indicated the bactericidal activity against Escherichia coli. After they were incubated with zymosan, the carp and black sea bream sera lost the activity completely, but the tilapia serum was not affected at all. EDTA entirely inhibited the bactericidal activity of all sera tested. While the carp and tilapia sera exhibited the bactericidal activity in the presence of EGTA, the others partially lost the activity. None of the sera used possessed antibody against E. coli. The bactericidal reaction of fish serum appeared to be owing mainly to the alternative pathway of complement, but the activation system of the alternative pathway of fish complement is probably different in each fish species.<BR>The bactericidal activity of the sera was lower against fish pathogens, Vibrio anguillarum and Edwardsiella tarda, than against E. coli.

Journal

  • Fish Pathology

    Fish Pathology 18(2), 77-83, 1983

    The Japanese Society of Fish Pathology

Cited by:  1

Codes

  • NII Article ID (NAID)
    130000859153
  • NII NACSIS-CAT ID (NCID)
    AN00063165
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    0388-788X
  • NDL Article ID
    2605704
  • NDL Source Classification
    RB96(水産--水産病理・水産保護)
  • NDL Source Classification
    ZR4(科学技術--生物学--動物)
  • NDL Call No.
    Z18-994
  • Data Source
    CJPref  NDL  J-STAGE 
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