原発性肝癌の病理形態学的研究

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  • 川畑 清春
    久留米大学医学部病理学教室第1講座 久留米大学医学部小児科教室

書誌事項

タイトル別名
  • Pathomorphological studies on hepatocellular carcinoma
  • ゲンパツセイ カンガン ノ ビョウリ ケイタイガクテキ ケンキュウ チョメイ
  • A study of the lymphnode with marked metastasis of hepatocellular carcinoma
  • 著明なリンパ節転移を示した肝細胞癌を中心に

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抄録

A pathomorphological study was carried out on 12 cases of hepatocellular carcinoma (HCC) with marked lymphnode metastasis among 154 HCC cases, autopsied at the Department of Pathology, Kurume University School of Medicine from January 1974 to August 1978.<BR>The results obtained were as follows;<BR>1) Metastasis was seen in the peripancreatic, the periportal and the periaortic lymphnode, in ordor of frequency.<BR>2) According to gross classification of HCC (Nakashima & Sakamoto's), infiltrative type of 4 cases, multinodular type of one case and mixed type of 7 cases were seen.<BR>3) Histologically, Edmondson's grade II of 5 cases, grade II-III of 2 cases, grade III of 4 cases and grade IV of one case were seen.<BR>4) Metastatic HCC in the lymphnodes were histological classified into two groups: island cell type and free cell type. Tumor cells of island cell type were cohesive in each other and formed island. Tumor cells of free cell type were non-cohesive and showed loose arrangement.<BR>5) Albumin positive cells were highly seen in metastasized HCC in the lymphnodes (81.8%) using immunoperoxidase (PAP) technique On the other hand, Alphafetoprotein positive cells were seen in only 18.2% of metastasized HCC in the lymphnodes.

収録刊行物

  • 肝臓

    肝臓 21 (2), 203-215, 1980

    一般社団法人　日本肝臓学会

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