硬化型肝細胞癌の臨床病理学的検討

• 伊波 勇人

  久留米大学第1病理学

書誌事項

タイトル別名

• Clinicopathological study on scirrhous hepatocellular carcinoma. A study of 12 resected cases.

抄録

Clinicopathological features of 12 resected cases of scirrhous hepatocellular carcinoma (HCC) was studied and compared with those of 307 cases of non-scirrhous type of HCC as the control group.<BR>In comparison with the control group, the prevalence of HBsAg positive was significantly higher in scirrhous-HCC (41.7%) than in the control group (18.2%). There was no significant difference in age, sex, pre-operative data of blood biochemistry and tumor markers. Although there was no significant difference in survival rate, the confirmed recurrence rates were 8.3% in scirrhous-HCC and 55.2% in the control group, respectively, with significant difference. Thus, it was assumed that the prognosis of scirrhous-HCC is better than that of common type of HCC.<BR>Pathomorphological studies revealed that scirrhous-HCC often showed the feature of central fibrous scars (58.3%). Microscopically, scirrhous-HCC was characterized by the presence of fibrous connective tissue along the blood space. Some other characteristics features of scirrhous-HCC included abscence of capsule (100%), presence of portal tracts (75.0%) and varying degrees of lymphocytic infiltration (75.0%) within the tumor nodule. In addition, the scirrhous-HCCs were frequently observed in Mallory bodies and pale bodies with a statistical significance.

収録刊行物

• 肝臓

  肝臓 35 (12), 855-863, 1994

  一般社団法人　日本肝臓学会

キーワード

• 硬化型肝細胞癌
• 肝細胞癌

詳細情報

• CRID: 1390001204788966656
• NII論文ID: 130000877407
• DOI: 10.2957/kanzo.35.855
• ISSN: 18813593
• ISSN: 04514203
• ISSN: http://id.crossref.org/issn/04514203
• Web Site: http://www.jstage.jst.go.jp/article/kanzo1960/35/12/35_12_855/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1995129943
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可