肝細胞癌に対する肝区域性動脈門脈同時塞栓化学療法（セメント療法）

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  • Hepatic segmental chemoembolization from both artery and portal vein (cement therapy) in the treatment of hepatocellular carcinoma.

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If the amount of Lipiodol infused into th hepatic artery exceeds a certain level, Lipiodol flows into the portal vein. Utilizing this phenomenon, an anti-cancer agent, emulsified in Lipiodol, was infused via the haptic artery into the portal branch of the target segment, followed by Gelfoam injection to obstruct the segmental arterial branch. This segmental chemoembolization is called Cement therapy. Of the 4 cases of hepatocellular carcinoma in which heptectomy was performed after Cement therapy, all but one case (in which collateral supply was observed) showed complte necrosis of the main tumor and daughter nodules as well as infarction of the cancer-free region. In the follow-up of 41 cases of hepatocellular carcinoma after Cement therapy, CT revealed almost 100% retention of Lipiodol and hepatic scintigraphy discloed segmental uptake reduction. One- and two-year cumulative survival rates for these 41 cases were as high as 86.7% and 60.7%, respectively.

収録刊行物

  • 肝臓

    肝臓 31 (9), 1094-1099, 1990

    一般社団法人　日本肝臓学会

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