アスピリンと非ステロイド性消炎鎮痛薬との併用に関する調査  [in Japanese] Investigation into the Combination of Aspirin with Non-steroidal Anti-inflammatory Drugs  [in Japanese]

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Author(s)

    • 伊藤 直子 ITO Naoko
    • 東京薬科大学薬学部臨床薬効解析学教室 Department of Clinical Evaluation of Drug Efficacy, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
    • 横山 晴子 YOKOYAMA Haruko
    • 東京薬科大学薬学部臨床薬効解析学教室 Department of Clinical Evaluation of Drug Efficacy, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
    • 鈴木 優司 SUZUKI Yuji
    • 東海大学医学部付属八王子病院薬剤科 Department of Pharmacy, Tokai University Hachioji Hospital
    • 山田 安彦 YAMADA Yasuhiko
    • 東京薬科大学薬学部臨床薬効解析学教室 Department of Clinical Evaluation of Drug Efficacy, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences

Abstract

  It has been reported that non-steroidal anti-inflammatory drugs (NSAIDs) interact with aspirin to influence its antiplatelet effect. For example, there have been reported that the rate of platelet aggregation inhibition associated with aspirin was significantly decreased when ibuprofen was taken before administration of aspirin, as compared with aspirin alone. In this study, we investigated the prescriptions on combination of aspirin with NSAIDs. The subjects were consisted of 1212 patients who were prescribed aspirin in March, 2008 in Tokai University Hachioji Hospital. The patients prescribed combination of aspirin with NSAIDs were 8.1% and 18.6% of those were prescribed in the order of adminstration to induce drug interaction. The pharmacists should provide information about drug interactions of aspirin with NSAIDs to the doctors and patients, and it is necessary to pay attention of these interactions.<br>

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 131(7), 1073-1077, 2011

    The Pharmaceutical Society of Japan

Codes

  • NII Article ID (NAID)
    130000926996
  • NII NACSIS-CAT ID (NCID)
    AN00284903
  • Text Lang
    JPN
  • ISSN
    0031-6903
  • NDL Article ID
    11166952
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z19-411
  • Data Source
    NDL  J-STAGE 
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