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- Yoshino Fumihiko
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College Clinic of Anti-Aging Medicine, Kanagawa Dental College Hospital
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- Yoshida Ayaka
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College
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- Sugiyama Shuta
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College
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- Tokutomi Fumiaki
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College
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- Miyamoto Chihiro
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College
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- Maehata Yojiro
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College
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- Kobayashi Kyo
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College
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- Wada-Takahashi Satoko
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College
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- Maetani Takashi
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College
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- Okada Eizo
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College
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- Okada Yasue
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College
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- Komatsu Tomoko
- Division of Dentistry for Special Patients, Department of Clinical Care Medicine, Kanagawa Dental College
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- Takahashi Shun-Suke
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College
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- Wan Jianrong
- Fish Protein Laboratory, Research and Development Center, Suzuhiro Kamaboko Honten Corporation Limited
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- Lee Masaichi-Chang il
- Division of Pharmacology and ESR Laboratories, Department of Clinical Care Medicine, Kanagawa Dental College Clinic of Anti-Aging Medicine, Kanagawa Dental College Hospital
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抄録
Objective: In this study, the antioxidant properties of peptide from boiled fish paste (fish products peptide; FPP) supplement were investigated in middle-aged subjects.<br>Methods: The subjects who participated in this study were men and premenopausal women, aged between 30 and 50 years (39.6 ± 5.5 years). The subjects consumed 10 tablets/day (containing 0.9 g of total fish peptide) for 60 days. Pre- and post-supplementation, subjects underwent analysis by physical measurement, completed the Anti-Aging QOL Common Questionnaire, and were examined in terms of vascular features, blood biochemical and uric characteristics, and hormone and oxidative stress markers.<br>Results: After 60 days of supplementation with FPP, significant improvement was observed in serum lipid peroxide (LPO) (−16.2 %, p = 0.001). In terms of oxidative markers, 8-hydroxy-2’-deoxyguanosine (8-OHdG) showed a tendency to decrease; in addition, potential antioxidant (PAO) and serum total antioxidant status (STAS), as antioxidant properties, showed slight increases. Furthermore, highsensitivity C-reactive protein (hs-CRP) also exhibited a tendency to decrease.<br>Discussion: The results show that FPP might contribute to the prevention of lifestyle-related disease by regulating the balance of oxidative stress and improving arteriosclerosis with high oxidative stress.
収録刊行物
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- ＡＮＴＩ‐ＡＧＩＮＧ ＭＥＤＩＣＩＮＥ
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ＡＮＴＩ‐ＡＧＩＮＧ ＭＥＤＩＣＩＮＥ 8 (4), 48-52, 2011
一般社団法人 日本抗加齢医学会
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詳細情報 詳細情報について
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- CRID
- 1390001205293712768
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- NII論文ID
- 130000968342
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- ISSN
- 18822762
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
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- KAKEN
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- 抄録ライセンスフラグ
- 使用不可