書誌事項
- タイトル別名
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- Predictive studies of hepatic encephalopathy in patients with liver cirrhosis by oral glucose tolerance tests and blood ketone body ratios.
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抄録
Incidences of hepatic encephalopathy and mortality were surveyed in patients with liver cirrhosis for about two years after 75g oral glucose tolerance tests. Among four groups classified by glucose tolerance pattern, a group with diabetic pattern under 140mg/dl of fasting plasma glucose and high value of 2 hours plasma glucose (over 2.5 fold fasting value), was shown to have the highest incidence of hepatic encephalopathy and the highest mortality, and revealed the worst value in various tests of liver function. The high-risk group was explained to have a marked trend to induce hepatic encephalopathy due to low value of blood ketone body ratio (acetacetate/β-hydroxybutyrate) and serum amino acid imbalance. Thus, the glucose tolerance test was suggested to be an useful parameter for prediction of hepatic encephalopaty and mortality in patients with liver cirrhosis.<br>Severe disturbances of glucose metabolism were considered to be involved with hepatic encephalopathy in patients with liver cirrhosis.
収録刊行物
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- 日本消化器病学会雑誌
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日本消化器病学会雑誌 83 (12), 2538-2544, 1986
一般財団法人 日本消化器病学会