Garlicnin A from the Fraction Regulating Macrophage Activation of <i>Allium sativum</i>
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Garlicnin A (<b>1</b>), a new stable, sulfur-containing compound isolated from a fraction of the acetone extracts of <i>Allium sativum</i> L. garlic bulbs, showed the potential to suppress tumor cell proliferation by inhibiting the polarization of M2 alternatively activated macrophages, and its structure was characterized as 3,4-dimethyl-5-(4,5-dithia-1<i>E</i>,7-octadiene)-tetrahydrothiophene-2-sulfoxide-<i>S</i>-oxide, on the basis of the results of spectroscopic analysis results.
- Chemical and Pharmaceutical Bulletin
Chemical and Pharmaceutical Bulletin 59(11), 1340-1343, 2011
The Pharmaceutical Society of Japan