Garlicnin A from the Fraction Regulating Macrophage Activation of <i>Allium sativum</i>

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Author(s)

Abstract

Garlicnin A (<b>1</b>), a new stable, sulfur-containing compound isolated from a fraction of the acetone extracts of <i>Allium sativum</i> L. garlic bulbs, showed the potential to suppress tumor cell proliferation by inhibiting the polarization of M2 alternatively activated macrophages, and its structure was characterized as 3,4-dimethyl-5-(4,5-dithia-1<i>E</i>,7-octadiene)-tetrahydrothiophene-2-sulfoxide-<i>S</i>-oxide, on the basis of the results of spectroscopic analysis results.

Journal

  • Chemical and Pharmaceutical Bulletin

    Chemical and Pharmaceutical Bulletin 59(11), 1340-1343, 2011

    The Pharmaceutical Society of Japan

Codes

  • NII Article ID (NAID)
    130001274807
  • NII NACSIS-CAT ID (NCID)
    AA00602100
  • Text Lang
    ENG
  • ISSN
    0009-2363
  • NDL Article ID
    11291069
  • NDL Source Classification
    ZS51(科学技術--薬学) // ZP1(科学技術--化学・化学工業)
  • NDL Call No.
    Z53-D167
  • Data Source
    NDL  J-STAGE 
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