Clinicopathological studies on 13 cases of adenoid cystic carcinoma originating from the salivary gland.
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- YAJIMA Mikito
- Department of Dentistry and Oral Surgery, Shinshu University School of Medicine
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- MINEMURA Toshikazu
- Department of Dentistry and Oral Surgery, Shinshu University School of Medicine
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- NEBASHI Shuichiro
- Department of Dentistry and Oral Surgery, Shinshu University School of Medicine
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- SUNADA Osamu
- Department of Dentistry and Oral Surgery, Shinshu University School of Medicine
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- TAMURA Minoru
- Department of Dentistry and Oral Surgery, Shinshu University School of Medicine
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- KURASHINA Kenji
- Department of Dentistry and Oral Surgery, Shinshu University School of Medicine
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- TAKEDA Susumu
- Department of Dentistry and Oral Surgery, Shinshu University School of Medicine
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- KOTANI Akira
- Department of Dentistry and Oral Surgery, Shinshu University School of Medicine
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- YAMAZAKI Tadashi
- Department of Dentistry and Oral Surgery, Komoro Kousei General Hospital
Bibliographic Information
- Other Title
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- 唾液腺に発生した腺様嚢胞癌13例の臨床的ならびに病理組織学的検討
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Abstract
Thirteen cases of adenoid cystic carcinoma originating from the salivary gland treated in our Department from 1966 to 1987 were studied clinically and pathologically, in an attempt to clarify its correlation between clinical stage, histological grade and prognosis. Both sexes were almost equally represented (7 male and 6 female) and the patients ranged from 39 to 79 years old. The primary sites of the tumors were 7 submandibular gland, 4 palate, 1 parotid gland and 1 buccal mucosa. The cases were classified according to the TNM classification (UICC 1987) and the histological grading (Szanto et al. 1984).<BR>The results were defined as follows:<BR>1) It was suggested that the histological grade and the clinical behavior should be correlated to each other. The prognosis of patients with the tumor of Grade III and Stage IV was most poor. All of these patients died of distant metastasis.<BR>2) In addition to histological grading, primary site, perineural invasion and bone invasion should be considered as other important factors. These findings appeared to be useful in predicting the prognosis.<BR>3) Patients with finding of positive surgical margin had the tendency that local recurrence was generated. Clinically, however, complete removal of the primary tumor was difficult, especially in the minor salivary gland. The planned combination of surgery and irradiation, adjuvant immunochemotherapy and multidisciplinary therapy should be considered.
Journal
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- Japanese Journal of Oral and Maxillofacial Surgery
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Japanese Journal of Oral and Maxillofacial Surgery 34 (8), 1716-1722, 1988
Japanese Society of Oral and Maxillofacial Surgeons
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Details 詳細情報について
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- CRID
- 1390001206533497984
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- NII Article ID
- 130001357155
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- ISSN
- 21861579
- 00215163
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed