Effects of Soluble and Insoluble Fiber Preparations Isolated from Oat, Barley, and Wheat on Liver Cholesterol Accumulation in Cholesterol-Fed Rats.
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- ODA Taishi
- Techmical Research Institute, Snow Brand Milk Products Department of Bioproduction Science, Faculty fo Horticulture, Chiba University
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- AOE Seiichiro
- Techmical Research Institute, Snow Brand Milk Products
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- SANADA Hiroo
- Department of Bioproduction Science, Faculty fo Horticulture, Chiba University
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- AYANO Yuko
- Department of Bioproduction Science, Faculty fo Horticulture, Chiba University
抄録
Effects of soluble and insoluble fiber preprations isolated from defatted oat, barley, and wheat on liver cholesterol accumulation were examined in cholesterol-fed rats. The soluble and insoluble fiber preparations were isolated by a modification of the procedure of Asp et al. Male Sprague-Dawley rats, aged 5 weeks, were fed a control diet containing 5% cellulose or diets containing soluble and insoluble fiber preparations for 9 days. Soluble fiber preparations from oat, barley, and wheat were added to diets corresponding to 1.9, 2.8, and 0.6% fiber, respectively. Insoluble fiber preparations from oat, barley, and wheat were added to diets corresponding to 3.1, 2.2, and 4.4% fiber, respectively. All of the soluble fiber preparations suppressed liver cholesterol accumula-tion, but they did not suppress the elevation of plasma cholesterol concen-trations. A significant inverse relationship between the quantity of ingest-ed soluble fiber and liver cholesterol accumulation was observed; n=28, r=-0.943, p<0.0001. None of the insoluble fiber preparations had any significant effect on liver and plasma cholesterol concentrations. These results indicate that the water-soluble fractions of oat, barley, and wheat are the active components that suppressed liver cholesterol accumulation, and that these effects are related to the quantity of ingested soluble fiber.
収録刊行物
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- Ｊｏｕｒｎａｌ ｏｆ Ｎｕｔｒｉｔｉｏｎａｌ Ｓｃｉｅｎｃｅ ａｎｄ Ｖｉｔａｍｉｎｏｌｏｇｙ
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Ｊｏｕｒｎａｌ ｏｆ Ｎｕｔｒｉｔｉｏｎａｌ Ｓｃｉｅｎｃｅ ａｎｄ Ｖｉｔａｍｉｎｏｌｏｇｙ 39 (1), 73-79, 1993
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