Effects of Fructooligosaccharides on the Absorption of Magnesium in the Magnesium-Deficient Rat Model.
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- OHTA Atsutane
- Bio Science Laboratories, Meiji Seika Kaisha, Ltd.
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- BABA Seigo
- Bio Science Laboratories, Meiji Seika Kaisha, Ltd.
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- TAKIZAWA Toshio
- Bio Science Laboratories, Meiji Seika Kaisha, Ltd.
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- ADACHI Takashi
- Bio Science Laboratories, Meiji Seika Kaisha, Ltd.
抄録
Magnesium (Mg) is an essential dietary element that plays important roles, acting as a cofactor of many enzymes. Rats fed a Mg-deficient diet have been reported to exhibit auricular and facial peripheral hyperemia and hemorrhage. Moreover, increased intake of calcium (Ca) or phosphorus (P) has been reported to impair apparent absorption of Mg. We tried to induce such typical inflammation in Mg-deficient rats by feeding low-Mg, high-Ca, and high-P diets. Increas-ing concentrations of Ca or P in the experimental diets significantly decreased the apparent absorption of Mg. And all rats fed the low-Mg (0.25mg/g diet), high-Ca (10.4mg/g diet), and high-P (12.0mg/g diet) diet exhibited auricular and facial peripheral.hyperemia and hemorrhage. Then, we used the low-Mg, high-Ca, and high-P diet to investigate the effects of the fructooligosaccharides (FO) on absorption of Mg and skin inflammation. In the rats fed FO-containing (1 or 5%) diet, apparent absorption of Mg was significantly increased as compared with that of the control (FO 0%) group. In the rats fed a 5% FO-containing diet and sufficient Mg (0.50mg/g), auricular and facial peripheral hyperemia and hemorrhage were significantly reduced. We concluded that FO increased the Mg absorption in rats fed a low-Mg, high-Ca, and high-P diet. Moreover, FO reduced inflammation in Mg-deficient rats, such as periph-eral hyperemia and hemorrhage.
収録刊行物
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- Ｊｏｕｒｎａｌ ｏｆ Ｎｕｔｒｉｔｉｏｎａｌ Ｓｃｉｅｎｃｅ ａｎｄ Ｖｉｔａｍｉｎｏｌｏｇｙ
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Ｊｏｕｒｎａｌ ｏｆ Ｎｕｔｒｉｔｉｏｎａｌ Ｓｃｉｅｎｃｅ ａｎｄ Ｖｉｔａｍｉｎｏｌｏｇｙ 40 (2), 171-180, 1994
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