書誌事項
- タイトル別名
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- Heat-killed lactobacillus casei, LC-9018, as an interferon inducer.
- ニュウサン カンキン LC-9018 ノ インターフェロン ユウキノウ
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抄録
A viral inhibitory activity was found in sera of ddY mice treated intraperitoneally with heat-killeld Lactobacillus casei LC-9018, at doses of 0.78-200mg/kg. The activity was ascribed to interferon(s) (IFN). A significant IFN activity of the sera of mice appeared in 18 hours and it reached a peak between 18-24 hours after the stimulation. In vitro treatment with anti-IFNγ antiserum neutrarized 67% of the IFN activity. The IFN-inducing activity of LC-9018 was diminished when mice were pretreated with monoclonal anti-Thy1, 2 antibody or carrageenan. These results suggest that T-cells and macrophages may be required for IFN induction with LC-9018.
収録刊行物
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- 日本細菌学雑誌
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日本細菌学雑誌 43 (4), 821-827, 1988
日本細菌学会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390282681426228224
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- NII論文ID
- 130001386128
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- NII書誌ID
- AN00189800
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- ISSN
- 18824110
- 00214930
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- NDL書誌ID
- 3200397
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- PubMed
- 3266256
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可