Ｍｅｔｈｉｃｉｌｌｉｎ　ｒｅｓｉｓｔａｎｔ　Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ　ａｕｒｅｕｓに対するカテキンの抗菌・殺菌作用

• 戸田 真佐子

  昭和大学医学部細菌学教室

• 大久保 幸枝

  昭和大学医学部細菌学教室

• 原 征彦

  三井農林株式会社食品総合研究所

• 島村 忠勝

  昭和大学医学部細菌学教室

書誌事項

タイトル別名

• Antibacterial and bactericidal activities of tea extracts and catechins against methicillin resistant Staphylococcus aureus.
• Methicillin resistant Staphylococcus au

抄録

We examined tea extract, (-) epigallocatechin gallate (EGCg) and theaflavin digallate (TF3) for their antibacterial and bactericidal activities against methicillin resistant Staphylococcus aureus (MRSA) and food poisoning strains of S. aureus. Twenty percent tea extract (50μl), EGCg (63μg) and TF3 (125μg) added to one ml of culture medium each inhibited the growth of all strains of MRSA and food poisoning S. aureus tested. Tea extract showed also a bactericidal activity against MRSA even at the same concentration of as in ordinarily brewed tea. EGCg at a concentration of 250μg/ml showed a bactericidal activity against MRSA but not against food poisoning S. aureus, but at 500μg/ml reduced markedly the viable number within 48h. These results suggest that tea and catechin can be used as prophylactic agents against MRSA infection.

収録刊行物

• 日本細菌学雑誌

  日本細菌学雑誌 46 (5), 839-845, 1991

  日本細菌学会

キーワード

• General Medicine

詳細情報

• CRID: 1390001206450239104
• NII論文ID: 130001386680
• NII論文ID: 10005470285
• NII書誌ID: AN00189800
• DOI: 10.3412/jsb.46.839
• COI: 1:CAS:528:DyaK38XhsVyjsbo%3D
• ISSN: 18824110
• ISSN: 00214930
• ISSN: http://id.crossref.org/issn/00214930
• NDL書誌ID: 3750332
• PubMed: 1762174
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I3750332
• Web Site: https://search.jamas.or.jp/link/ui/1993241057
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可