Plasma ADH(antidiuretic hormone) in patients with pulmonary tuberculosis.
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- NAKAMATA Masami
- Department of pulmonary disease, National Sanatorium Nishi-Niigata Hospital
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- TSUKIOKA Kazuharu
- Department of pulmonary disease, National Sanatorium Nishi-Niigata Hospital
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- KONDO Ariyoshi
- Department of pulmonary disease, National Sanatorium Nishi-Niigata Hospital
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- HASHIMOTO Tadashi
- Department of pulmonary disease, National Sanatorium Nishi-Niigata Hospital
Bibliographic Information
- Other Title
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- 肺結核症における抗利尿ホルモン（ＡＤＨ）について
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Abstract
We studied plasma ADH (antidiuretic hormone) in 92 patients with pulmonary tuberculosis.Abnormally high plasma ADH was observed in 27 patients. PaO2 was less than 60mmHg in 25 out of these 27 patients, and other 2 had wide spread tuberculous lesion. Abnormally high plasma ADH was observed more frequently in the patients with hypercapnic acidosis than in the patients with eucapnic respiratory failure. In the majority of the patients, relation between osmotic pressure and ADH was in the reasonable range. There was no relation between plasma ADH and activity of pulmonary tuberculosis.<BR>It was suggested that abnormally high plasma ADH in the patients with pulmonary tuberculosis was caused mainly by the reaction against abnormal arterial blood gases and partially by reduced blood flow in the pulmonary vessels damaged by tuberculosis or by respiratory failure.<BR>2 patients were suspected of SIADH (syndrome of inappropriate secretion of ADH), although abnormally high plasma renin activity was observed in 2 patients. Furthermore, high plasma ADH may thought to be a reaction. Therefore some discussion will be required that these patients are true SIADH or not.
Journal
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- Kekkaku(Tuberculosis)
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Kekkaku(Tuberculosis) 62 (12), 635-639, 1987
JAPANESE SOCIETY FOR TUBERCULOSIS
