書誌事項
- タイトル別名
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- LIVER DYSFUNCTION INDUCED BY RIFAMPICIN
- RFP ニヨル カン ショウガイ
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抄録
Rifampicin (RFP)-induced liver dysfunction during the treatment for tuberculosis was discussed.<BR>Incidence of RFP-induced liver dysfunction was 11.1 % (151 cases) among 1, 359 cases treatedwith RFP-containing regimens.<BR>Many of the RFP-induced liver dysfunction were observed in the early stage of chemotherapy, and the elevation of serum transaminases (s-GOT and s-GPT) was mild in the majority of cases. Asthe recovery was retarded among cases with s-transaminases above 100 K-U than cases below 100, the former RFP should be discontinued in the former until the restoration of liver dysfunction.<BR>Attention should be payed to the cases with elevated s-transaminases combined with abnormalitiesof other laboratory data such as ZnTT, history of other liver dysfunction, diabetes mellitus or habitualdrinkings, as the recovery of liver dysfunction is retarded in such cases.<BR>The liver dysfunction as one of the side-effects should be given proper attention in the treatmentfor tuberculosis, considering long-term benefit of patients.
収録刊行物
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- 結核
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結核 57 (4), 257-261, 1982
一般社団法人 日本結核病学会
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詳細情報 詳細情報について
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- CRID
- 1390282679976904832
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- NII論文ID
- 130001416751
- 10004929971
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- NII書誌ID
- AN00073442
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- ISSN
- 18842410
- 00229776
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- NDL書誌ID
- 2487696
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- PubMed
- 7109426
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可