Filtration system for continuous thoracic duct drainage.

DOI

Bibliographic Information

Other Title
  • 胸管ドレナージ用リンパろ過システム

Abstract

Thoracic duct drainage has been clinically used for correction of immunological disorders such as autoimmune diseases and rejection in kidney transplantation. However, although clinical usefulness has been so advocated, actual applications have been very much limitted probably due to complexity in its maneuver. In an attempt to solve the problem, a novel thoracic duct drainage system which utilizes continuous filtration of lymphatic fluid to collect lymphocytes has been newly devised. The system is composed of a fine doublelumen catheter and a wearable pump for drainage, a filter (CPC-1 IFC) for lymphocyte trapping and a small infusion pump for heparin injection. A preliminary in vitro experiment evidenced reliability of the function of the system. An animal experiment using mongrel dogs showed that a lymph flow rate was 40 to 90ml/hr and all lymphocytes flowing from the thoracic duct which was counted 2.0 to 4.3×106/ml were caught by the filter. Total portein concentration in lymphatic fluid did not change even after the filtration. In conclusion, the system is proved to be simple and reliable to collect lymphocytes and expected to be applicable for clinical use.

Journal

  • Jinko Zoki

    Jinko Zoki 16 (2), 1007-1010, 1987

    JAPANESE SOCIETY FOR ARTIFICIAL ORGANS

Keywords

Details 詳細情報について

  • CRID
    1390282679935495680
  • NII Article ID
    130001734791
  • DOI
    10.11392/jsao1972.16.1007
  • ISSN
    18836097
    03000818
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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