小口径代用血管の端側吻合部における変化

DOI

書誌事項

タイトル別名
  • An experimental study of intimal hyperplasia (AIH) developing at the end-to-side anastomosis in small caliber vascular graft.

抄録

The present experimental study was undertaken to investigate the precise location and progression of AIH at the end-to-side anastomosis and its relationship to flow disturbance. An aorto (end-to-end anastomosis)-iliac (end-to-side anastomosis) bypass was made in 30 dogs using 22 Biografts, 3 EPTFE and 5 Dacron grafts. Distal end-to-side anastornoses were formed at 3 different angles, i. e. 30° (Group I, n=14), 90° (Group II, n=5) and 150° (Group III, n=15), to obtain 3 different patterns of flow dynamics. AIH occured in 4 cases of Group I and 1 of Group II. All these AIH grew from the toe where Boundary Layer Separation (BLS) was being Provoked. In Group III, a slight degree of AIH was seen in only 1 case at 24 months after implantation. Thus, unduly increased runoff into the heel in an end-to-side anastomosis may lead to the formation of extensive BLS at the toes, which, in tern, is causative of AIH. In Biograft, the forefront of AIH was observed peeling off and characteristically laden with a thrombus. On the other hand, in EPTFE, AIH was organized competely and formed with a gentle slope along the blood stream. Graft occlusion may result largely from accretion of piles of thrombus formed at the forefront of pannus, in the case of smooth surface materlal such as Biograft.

収録刊行物

  • 人工臓器

    人工臓器 16 (3), 1457-1460, 1987

    一般社団法人 日本人工臓器学会

詳細情報 詳細情報について

  • CRID
    1390282679934647552
  • NII論文ID
    130001734976
  • DOI
    10.11392/jsao1972.16.1457
  • ISSN
    18836097
    03000818
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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