Effect of sulpiride (Dogmatyl) on abnormal sensation in the throat.

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  • Sulpirideによるいんこう頭異常感症の治療成績

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Abstract

Fifty-one male and 53 female patients with abnormal sensation in the throat were treated orally for two weeks with sulpiride (Dogmatyl®), and the therapeutic effect was evaluated one and two weeks after the start of treatment and one week after its termination. It was considered to be effective when the abnormal sensation improved subjectively by 50% or more. In one of the 104 patients, side effects were so severe that the medication had to be discontinued. In the remaining 103 patients, the medication was effective in 56% at one week, in 66% at two weeks and in 61% at three weeks. The rate of complete cure was significantly higher in patients with depression (53%) than in nondepressed patients (19%).

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