Norfloxacin treatment of chronic sinusitis.

• Masuda Masuda

  Mie University

• Majima Yuichi

  Mie University

• Inagaki Masashi

  Mie University

• Saida Satoshi

  Mie University

• Sakakura Yasuo

  Mie University

Bibliographic Information

Other Title

• ＮＦＬＸの慢性副鼻腔炎に対する効果

Abstract

This study was designed to determine the effectiveness of norfloxacin (NFLX), a new quinolonecarboxylic acid analogue, on the symptoms and signs of chronic sinusitis. The subjects of this study were 14 patients aged 13 to 71 years, who received NFLX 600mg per day p. o. for 2 weeks. Neither antiinflammatory nor mucolytic agents were given.<br>The effectiveness of NFLX on the subjective symptoms and rhinoscopic observations was 64.3%. X-ray opacity of the maxillary sinus was evaluated with a microdensitometer. The pre- and post- treatment data were compared in 13 patients (26 maxillary sinuses). Improvement of X-ray opacities by NFLX treatment was noted in 23.1 %. The general effectiveness of NFLX on the subjective symptoms, rhinoscopic observations and X-ray opacity was 65.4%. No side effects were noted.

Journal

• Practica Oto-Rhino-Laryngologica

  Practica Oto-Rhino-Laryngologica 82 (3), 471-478, 1989

  The Society of Practical Otolaryngology

Keywords

• chronic sinusitis
• Norfloxacin
• X-ray opacity (M/O ratio)

Details

• CRID: 1390001204262836352
• NII Article ID: 130001811168
• DOI: 10.5631/jibirin.82.471
• ISSN: 18844545
• ISSN: 00326313
• Web Site: https://search.jamas.or.jp/link/ui/1990146071
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed