Annonamine, a New Aporphine Alkaloid from the Leaves of Annona muricata
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Atypical Parkinsonism in the Caribbean Island Guadeloupe is thought to be associated with the consumption of plants of the Annonaceae family, especially <i>Annona muricata</i> (soursop). In this study, a new aporphine alkaloid named annonamine (<b>1</b>) was isolated from the leaves of <i>A. muricata</i> L. together with four known benzylisoquinoline alkaloids (<b>2</b>—<b>5</b>). The structures of the isolated compounds were elucidated by the spectroscopic method.
- Chemical and Pharmaceutical Bulletin
Chemical and Pharmaceutical Bulletin 60(2), 257-259, 2012
The Pharmaceutical Society of Japan