Indomethacin Induction of Metamorphosis from the Asexual Stage to Sexual Stage in the Moon Jellyfish, <i>Aurelia aurita</i>

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Author(s)

    • KUNIYOSHI Hisato KUNIYOSHI Hisato
    • Faculty of Applied Biological Science, Graduate School of Biosphere Science, Hiroshima University|Faculty of Applied Biological Science, Graduate School of Biosphere Science, Hiroshima University
    • OKUMURA Izumi OKUMURA Izumi
    • Faculty of Applied Biological Science, Graduate School of Biosphere Science, Hiroshima University|Faculty of Applied Biological Science, Graduate School of Biosphere Science, Hiroshima University
    • KURODA Rie [他] KURODA Rie
    • Faculty of Applied Biological Science, Graduate School of Biosphere Science, Hiroshima University|Faculty of Applied Biological Science, Graduate School of Biosphere Science, Hiroshima University
    • TSUJITA Natsumi
    • Faculty of Applied Biological Science, Graduate School of Biosphere Science, Hiroshima University|Faculty of Applied Biological Science, Graduate School of Biosphere Science, Hiroshima University
    • ARAKAWA Kenji
    • Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University|Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University
    • SHOJI Jun
    • Faculty of Applied Biological Science, Graduate School of Biosphere Science, Hiroshima University|Faculty of Applied Biological Science, Graduate School of Biosphere Science, Hiroshima University
    • SAITO Tamio
    • Chemical Biology Core Facility, RIKEN Advanced Science Institute|Chemical Biology Core Facility, RIKEN Advanced Science Institute
    • OSADA Hiroyuki
    • Chemical Biology Core Facility, RIKEN Advanced Science Institute|Chemical Biology Core Facility, RIKEN Advanced Science Institute

Abstract

We found while screening a chemical library that indomethacin, an inhibitor of prostaglandin biosynthesis, induced strobilation (metamorphosis from the asexual to sexual stage) in the moon jellyfish, <i>Aurelia aurita</i>. Indomethacin initiated strobilation in a dose-dependent manner, but was not involved in the progression of strobilation. Pharmacological experiments suggested that indomethacin could induce strobilation independently of prostaglandin biosynthesis.

Journal

  • Bioscience, Biotechnology, and Biochemistry

    Bioscience, Biotechnology, and Biochemistry 76(7), 1397-1400, 2012

    Japan Society for Bioscience, Biotechnology, and Agrochemistry

Codes

  • NII Article ID (NAID)
    130001862721
  • NII NACSIS-CAT ID (NCID)
    AA10824164
  • Text Lang
    ENG
  • ISSN
    0916-8451
  • NDL Article ID
    023841187
  • NDL Call No.
    Z53-G223
  • Data Source
    NDL  J-STAGE 
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