Metal-free Direct Biaryl Coupling Reaction of Heteroaromatic Compounds <i>via</i> Iodonium Intermediate
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- MORIMOTO Koji
- College of Pharmaceutical Sciences, Ritsumeikan University
Bibliographic Information
- Other Title
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- 遷移金属触媒を用いないヘテロ芳香族化合物のクロスカップリング反応の開発
- センイ キンゾク ショクバイ オ モチイナイ ヘテロ ホウコウゾク カゴウブツ ノ クロスカップリング ハンノウ ノ カイハツ
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Abstract
Biaryl compounds are versatile building blocks in the synthesis of natural products, pharmaceuticals, agricultural chemicals and π-conjugated organic materials. This review describes a recent progress for the biaryl cross-coupling reaction of heteroaromatic compounds using hypervalent iodine reagent. Our novel biaryl coupling reaction is a unique method for constructing various heteroaromatic biaryls without use of transition metal catalysts. From mechanistic point of view, the coupling reaction was realized through stable iodine intermediate generated from heteroaroamatic compound and iodine (III) reagent.<br>
Journal
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- YAKUGAKU ZASSHI
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YAKUGAKU ZASSHI 131 (9), 1339-1345, 2011-09-01
The Pharmaceutical Society of Japan
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Details 詳細情報について
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- CRID
- 1390001206127876992
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- NII Article ID
- 130001871941
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- NII Book ID
- AN00284903
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- ISSN
- 13475231
- 00316903
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- NDL BIB ID
- 11222521
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- PubMed
- 21881309
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed