Daily CT Measurement of Needle Applicator Displacement during Multifractionated High-dose-rate Interstitial Brachytherapy for Postoperative Recurrent Uterine Cancer

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Author(s)

    • YOSHIDA Ken YOSHIDA Ken
    • Department of Radiation Oncology, National Hospital Organization Osaka National Hospital|Institute for Clinical Research, National Hospital Organization Osaka National Hospital
    • TAKENAKA Tadashi
    • Department of Radiology, National Hospital Organization Osaka National Hospital
    • KOTSUMA Tadayuki
    • Department of Radiology, National Hospital Organization Kinki-Chuo Chest Medical Center
    • ARAMOTO Kazumasa
    • Department of Radiology, National Hospital Organization Osaka National Hospital
    • MIYAKE Shunsuke
    • Department of Radiology, National Hospital Organization Osaka National Hospital
    • KORETSUNE Yukihiro
    • Institute for Clinical Research, National Hospital Organization Osaka National Hospital
    • BAN Chiaki
    • Department of Obstetrics and Gynecology, National Hospital Organization Osaka National Hospital

Abstract

We investigated daily needle applicator displacement during multifractionated high-dose-rate interstitial brachytherapy (HDR-ISBT) for postoperative recurrent uterine cancer. Eight patients with postoperative recurrent uterine cancer received HDR-ISBT with or without external beam radiotherapy using our unique ambulatory technique. To analyze displacement, we obtained daily computed tomography (CT) images for 122 flexible needle applicators at 21, 45, 69, and 93 hours after implantation. Displacement was defined as the length between the center of gravity of titanium markers and the needle applicator tips along the daily CT axis. For cases in which displacement was not corrected, we also calculated the dose that covered 90% of the clinical target volume (D90(CTV)) using a dose–volume histogram (DVH). Median caudal needle applicator displacement at 21, 45, 69, and 93 hours was 3, 2, 4, and 5 mm, respectively. More than 15 mm displacement was observed for 2% (2 of 122) and 17% (10 of 60) of needle applicators at 21 and 93 hours, respectively. Cases in which dwell positions were not changed to correct the treatment plan, 2 of 8 patients showed more than 10% reduction in D90(CTV) values compared with the initial treatment plan. Correction of dwell positions of the treatment source improves treatment DVH for multifractionated HDR-ISBT.

Journal

  • Journal of Radiation Research

    Journal of Radiation Research 53(2), 295-300, 2012

    Journal of Radiation Research Editorial Committee

Codes

  • NII Article ID (NAID)
    130001876841
  • NII NACSIS-CAT ID (NCID)
    AA00705792
  • Text Lang
    ENG
  • ISSN
    0449-3060
  • NDL Article ID
    023572281
  • NDL Call No.
    Z53-P232
  • Data Source
    NDL  J-STAGE 
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