Pulmonary Veno-occlusive Disease Following Reduced-intensity Allogeneic Bone Marrow Transplantation for Acute Myeloid Leukemia
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- Hosokawa Kohei
- Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Japan
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- Yamazaki Hirohito
- Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Japan
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- Nishitsuji Masaru
- Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Japan
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- Kobayashi Satoshi
- Department of Radiology, Kanazawa University School of Medicine, Japan
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- Takami Akiyoshi
- Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Japan
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- Fujimura Masaki
- Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Japan
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- Nakao Shinji
- Cellular Transplantation Biology, Kanazawa University Graduate School of Medical Science, Japan
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We report a case of pulmonary veno-occlusive disease (PVOD) following allogeneic bone marrow transplantation (BMT) for the treatment of acute myeloid leukemia (AML) from an HLA mismatched mother using a reduced-intensity conditioning (RIC) regimen including gemtuzumab ozogamicin. The patient was a 21-year-old male who complained of dyspnea with hypoxemia followed by loss of consciousness. The abnormalities in chest CT and echocardiography were compatible with a diagnosis of PVOD. Treatment with 1 mg/kg of oral prednisolone resolved dyspnea and hypoxemia within a few days, and chest CT abnormalities disappeared in a week. This report is the first to describe PVOD following RIC stem cell transplantation.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 51 (2), 195-198, 2012
一般社団法人 日本内科学会
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詳細情報 詳細情報について
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- CRID
- 1390282679847013888
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- NII論文ID
- 130002062063
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- NII書誌ID
- AA10827774
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- ISSN
- 13497235
- 09182918
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- Crossref
- CiNii Articles
- KAKEN
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