A Case of Combined Sarcoidosis and Usual Interstitial Pneumonia

  • Tachibana Kazunobu
    Department of Diffuse Lung Diseases and Respiratory Failure, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan Department of Respiratory Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan
  • Arai Toru
    Department of Diffuse Lung Diseases and Respiratory Failure, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan Department of Respiratory Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan
  • Kagawa Tomoko
    Department of Respiratory Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan
  • Minomo Shojiro
    Department of Respiratory Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan
  • Akira Masanori
    Department of Radiology, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan
  • Kitaichi Masanori
    Department of Pathology, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan
  • Inoue Yoshikazu
    Department of Diffuse Lung Diseases and Respiratory Failure, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan

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抄録

Sarcoidosis is a systemic granulomatous disease of unknown etiology with characteristic pulmonary lesions, which are often distributed in the upper lung fields. We describe a unique case of sarcoidosis with lower lung field-dominant reticular shadows. Three years after the diagnosis of sarcoidosis based on histologic findings of the mediastinal lymph nodes and transbronchial lung biopsy specimens, the patient developed acute respiratory failure and died. The autopsy showed usual interstitial pneumonia (UIP), with honeycombing and superimposed diffuse alveolar damage of the lungs. The findings suggest that the patient had both sarcoidosis and UIP, and that the UIP later progressed to acute exacerbation.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 51 (14), 1893-1897, 2012

    一般社団法人 日本内科学会

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