Effective Use of Gemcitabine in the Treatment of Undifferentiated Carcinoma with Osteoclast-Like Giant Cells of the Pancreas with Portal Vein Tumor Thrombus
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- Yoshioka Masato
- Department of Gastroenterological Surgery, Akita University Graduate School of Medicine, Japan
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- Uchinami Hiroshi
- Department of Gastroenterological Surgery, Akita University Graduate School of Medicine, Japan
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- Watanabe Go
- Department of Gastroenterological Surgery, Akita University Graduate School of Medicine, Japan
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- Takahashi Tomokazu
- Department of Gastroenterological Surgery, Akita University Graduate School of Medicine, Japan
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- Nakagawa Yasuhiko
- Department of Gastroenterological Surgery, Akita University Graduate School of Medicine, Japan
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- Andoh Hideaki
- Department of Gastroenterological Surgery, Akita University Graduate School of Medicine, Japan
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- Yoshioka Toshiaki
- Department of Pathology, Akita University School of Medicine, Japan
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- Nanjo Hiroshi
- Department of Pathology, Akita University School of Medicine, Japan
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- Yamamoto Yuzo
- Department of Gastroenterological Surgery, Akita University Graduate School of Medicine, Japan
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抄録
A 74-year-old woman had an undifferentiated carcinoma with osteoclast-like giant cells (UCWOGC) in the body of the pancreas with massive portal vein tumor thrombus (PVTT). Because the PVTT progressed so rapidly into the right portal branch, the patient first underwent distal pancreatectomy and tumor thrombectomy to prevent life-threatening portal venous obstruction. Although a recurrent PVTT had developed early postoperatively, systemic gemcitabine treatment was so effective that it induced complete remission 5 months after the initiation of chemotherapy. The patient continued to be in complete response for 12 months, and has survived for 19 months since surgery.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 51 (16), 2145-2150, 2012
一般社団法人 日本内科学会