Slowly Progressive Insulin-Dependent Diabetes in a Patient with Primary Biliary Cirrhosis with Portal Hypertension-Type Progression
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- Takeshita Yumie
- Department of Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Science, Japan
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- Takamura Toshinari
- Department of Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Science, Japan
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- Inoue Oto
- Department of Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Science, Japan
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- Okumura Miki
- Department of Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Science, Japan
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- Kato Kenichiro
- Department of Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Science, Japan
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- Sunagozaka Hajime
- Department of Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Science, Japan
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- Arai Kuniaki
- Department of Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Science, Japan
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- Misu Hirofumi
- Department of Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Science, Japan
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- Nakamura Minoru
- National Hospital Organization (NHO) Nagasaki Medical Center and Department of Hepatology, Nagasaki University Graduate School of Biochemical Sciences, Japan
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- Nakanuma Yasuni
- Department of Human Pathology, Kanazawa University Graduate School of Medical Science, Japan
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- Kaneko Shuichi
- Department of Disease Control and Homeostasis, Kanazawa University Graduate School of Medical Science, Japan
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A 73-year-old woman had previously been diagnosed with CREST syndrome, PBC and diabetes. Hepatic fibrosis was not evident, in spite of the transudative ascites and active esophageal varices. ACA were positive, whereas AMA and anti-gp210 antibodies were negative. She showed low urinary excretion of C-peptide and was weakly positive for anti-GAD antibody. She was diagnosed with a form of PBC that progresses via portal hypertension rather than liver failure and with SPIDDM. Her HLA type did not contain risk allele for IDDM or PBC. SPIDDM should be considered when patients with PBC with portal hypertension-type progression develop diabetes.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 51 (1), 79-82, 2012
一般社団法人 日本内科学会
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詳細情報 詳細情報について
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- CRID
- 1390001204871715072
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- NII論文ID
- 130002062431
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- NII書誌ID
- AA10827774
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- ISSN
- 13497235
- 09182918
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可