Internal Medicine : Ehrlichia canis Infection in Two Dogs that Emigrated from Endemic Areas

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  • BABA Kenji
    Laboratory of Veterinary Parasitology, Department of Veterinary Medicine, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan
  • ITAMOTO Kazuhito
    Laboratory of Veterinary Clinical Diagnostics, Department of Veterinary Medicine, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan
  • AMIMOTO Akiteru
    Amica Pet Clinic, 3-3-2 Onda-Cho, Ube, Yamaguchi 755-0023, Japan
  • KITAGAWA Kozue
    Laboratory of Veterinary Parasitology, Department of Veterinary Medicine, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan
  • HIRAOKA Hiroko
    Laboratory of Veterinary Clinical Pathology Department of Veterinary Medicine, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan
  • MIZUNO Takuya
    Laboratory of Veterinary Internal Medicine, Department of Veterinary Medicine, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan
  • SATO Hiroshi
    Laboratory of Veterinary Parasitology, Department of Veterinary Medicine, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan
  • OKUDA Masaru
    Laboratory of Veterinary Internal Medicine, Department of Veterinary Medicine, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8515, Japan

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タイトル別名
  • <i>Ehrlichia canis</i> Infection in Two Dogs that Emigrated from Endemic Areas
  • Ehrlichia canis infection in two dogs that emigrated from endemic areas

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抄録

Two dogs, emigrated from Zambia and China to Japan, were diagnosed with Ehrlichia canis infection. Both cases had thrombocytopenia, non-regenerative anemia, and hypergloblinemia with polyclonal gammopathy. Case 1 had ataxia of the hind limbs. Severe meningitis was revealed by magnetic resonance imaging examination. Intracytoplasmic inclusions were observed in mononuclear cells of cerebrospinal fluid. Case 2 had a history of bilateral epistaxis, and severe pancytopenia was noticed in complete blood count. Diagnosis was finally achieved by nested polymerase chain reaction and sequence analysis. Thus, even in non-endemic areas, E. canis infection should be included in the differential diagnosis of clinically ill dogs that emigrated from endemic areas.

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