The possibility of antigenic peptide, protein and DNA delivery by percutaneous vaccination

• Seo Naohiro

  Department of Cancer Vaccine, Mie University Graduate School of Medicine

• Shiku Hiroshi

  Department of Cancer Vaccine, Mie University Graduate School of Medicine

Bibliographic Information

Other Title

• 経皮ペプチド、タンパク質、DNAワクチンデリバリーの実用化にむけて
• ケイヒ ペプチド 、 タンパクシツ 、 DNA ワクチンデリバリー ノ ジツヨウカ ニ ムケテ

Abstract

Skin is a leading candidate tissue in delivery system of peptide and protein including T-cell epitope sequence, and T-cell epitope-coding DNA because the dendritic cells which function as a powerful antigen-presenting cell for tumor- and pathogenic microorganism-specific T cell activation resides in epidermis and dermis of the skin. In this article, we describe the current topics of percutaneous vaccination for immunogenic antigen delivery.

Journal

• Drug Delivery System

  Drug Delivery System 27 (3), 194-201, 2012

  THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM

Keywords

• Cancer vaccine
• Epidermal Langerhans cell
• Skin immunity
• Cytotoxic T lymphocyte
• Corneum barrier

Details

• CRID: 1390282679617175296
• NII Article ID: 130002100515
• NII Article ID: 40019398992
• NII Book ID: AN10084591
• DOI: 10.2745/dds.27.194
• ISSN: 18812732
• ISSN: 09135006
• NDL BIB ID: 023913377
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I023913377
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed