Extracts of Common Buckwheat Bran Prevent Sucrose Digestion

Access this Article

Author(s)

    • HOSAKA Toshio
    • Department of Public Health and Applied Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School
    • SHUTO Emi
    • Department of Public Health and Applied Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School
    • OKAHISA Naoki
    • Food Technology Division, Tokushima Prefectural Industrial Technology Center
    • IWATA Shinya
    • Food Technology Division, Tokushima Prefectural Industrial Technology Center
    • SAKAI Tohru
    • Department of Public Health and Applied Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School
    • NII Yoshitaka
    • Food Technology Division, Tokushima Prefectural Industrial Technology Center
    • ITO Takahiro
    • Department of Public Health and Applied Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School
    • TAMANAHA Aya
    • Department of Public Health and Applied Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School
    • YAMASAKA Yukiko
    • Department of Public Health and Applied Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School
    • SASAGA Sayaka
    • Department of Public Health and Applied Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School
    • TSUTSUMI Rie
    • Department of Public Health and Applied Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School

Abstract

Buckwheat has been shown to have various health benefits such as reduction of hypertension and improvement of hypercholesterolemia; however, its effect on diabetes has not been fully elucidated. In this study, buckwheat bran extracts (BBE) inhibited sucrase activity in vitro more effectively than buckwheat. Balb/c mice pretreated with BBE showed dose-dependent reductions of blood glucose, greater than those observed with control mice, within 60 min following oral sucrose administration. Blood glucose levels in mice pretreated with buckwheat extracts were also significantly lower compared to those in control mice within 30 min following oral administration of sucrose. However, rutin, one of the abundant polyphenols of BBE, did not lower blood glucose level. Our data indicate that components of BBE other than rutin have inhibitory activity against sucrase in vivo. These results suggest that BBE could have beneficial effects on diabetes.

Journal

  • Journal of Nutritional Science and Vitaminology

    Journal of Nutritional Science and Vitaminology 57(6), 441-445, 2011

    Center for Academic Publications Japan

Codes

  • NII Article ID (NAID)
    130002103056
  • Text Lang
    ENG
  • ISSN
    0301-4800
  • Data Source
    J-STAGE 
Page Top