Sugar-Sensitive Supramolecular Structures Based on Phenylboronic Acid-Modified Cyclodextrins
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Supramolecular structures were developed from phenylboronic acid-modified cyclodextrins (PBA-CyDs). The intermolecular interaction between the PBA moiety and the CyD cavity was proved using two dimensional (2D)-NMR and powder X-ray diffraction techniques. PBA-α-CyD formed a head-to-tail supramolecular polymer, whereas PBA-β-CyD formed a head-to-head dimer. The supramolecular structures were disintegrated in the presence of sugars owing to the resulting boronate sugar interactions.
- Chemical and Pharmaceutical Bulletin
Chemical and Pharmaceutical Bulletin 61(11), 1188-1191, 2013
The Pharmaceutical Society of Japan