Chronic Inflammatory Demyelinating Polyradiculoneuropathy in a Patient with Crohn's Disease

  • Ohyagi Masaki
    Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Japan
  • Ohkubo Takuya
    Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Japan
  • Yagi Yousuke
    Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Japan
  • Ishibashi Satoru
    Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Japan
  • Akiyama Junko
    Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Japan
  • Nagahori Masakazu
    Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Japan
  • Watanabe Mamoru
    Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Japan
  • Yokota Takanori
    Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Japan
  • Mizusawa Hidehiro
    Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Japan

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抄録

Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract that is frequently accompanied by systemic complications. Neuropathologies have not been well investigated as extraintestinal manifestations of CD. We herein report the case of a 36-year-old man with CD who presented with progressive weakness and numbness. A neurological examination and the results of a nerve conduction study and a sural nerve biopsy led to a diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Plasma exchanges were initially effective; however, the effects gradually declined starting 10 days after the plasma exchange (PE). These results suggest that humoral factors may play an important role in CIDP associated with CD.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 52 (1), 125-128, 2013

    一般社団法人 日本内科学会

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