Two Patients with Antiphospholipid Antibody Developed Disseminated Intravascular Coagulation

  • Habe Koji
    Department of Dermatology, Mie University Graduate School of Medicine, Japan
  • Wada Hideo
    Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine, Japan
  • Ito-Habe Naomi
    Department of Hematology and Oncology, Mie University Graduate School of Medicine, Japan
  • Suzuki Hikoji
    Department of Internal Medicine, Suzuka Kaisei Hospital, Japan
  • Nobori Tsutomu
    Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine, Japan
  • Mizutani Hitoshi
    Department of Dermatology, Mie University Graduate School of Medicine, Japan

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Abstract

One hundred and eleven patients with antiphospholipid antibodies (aPL) were diagnosed at Mie University Hospital during the past 17 years. Two of these patients developed disseminated intravascular coagulation (DIC). The first patient twice developed DIC complicated by pancreatitis and pregnancy, while in the second case, no specific causative complications for DIC were identified. The details of these cases imply that aPL is associated with DIC and/or is a potent triggering factor for DIC.<br>

Journal

  • Internal Medicine

    Internal Medicine 52 (2), 269-272, 2013

    The Japanese Society of Internal Medicine

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