Prevalence and Risk Factors of Nasopharyngeal Carriage of Streptococcus pneumoniae in Healthy Children in Japan

DOI Web Site PubMed 参考文献11件
  • Ueno Masahiro
    Department of Environmental and Occupational Health, School of Medicine, Toho University Department of Pediatrics, Hasuda Issinkai Hospital
  • Ishii Yoshikazu
    Department of Microbiology and Infectious Diseases, School of Medicine, Toho University
  • Tateda Kazuhiro
    Department of Microbiology and Infectious Diseases, School of Medicine, Toho University
  • Anahara Yoshiko
    Department of Bacteriology, Ageo Medical Laboratories, Inc.
  • Ebata Akiko
    Department of Bacteriology, Ageo Medical Laboratories, Inc.
  • Iida Masaei
    Department of Bacteriology, Ageo Medical Laboratories, Inc.
  • Inamura Seiko
    Yashio Ekimae Internal Medicine and Pediatric Clinic
  • Takahata Kahori
    Department of Pediatrics, Tokyo Women's Medical University Medical Center East
  • Suzuki Yoko
    Department of Pediatrics, Tokyo Women's Medical University Medical Center East
  • Chang Bin
    Department of Bacteriology I, National Institute of Infectious Diseases
  • Wada Akihito
    Yonaguni Medical Clinic Department of Bacteriology I, National Institute of Infectious Diseases
  • Sugita Minoru
    Department of Environmental and Occupational Health, School of Medicine, Toho University
  • Tanaka Taichiro
    Department of Environmental and Occupational Health, School of Medicine, Toho University
  • Nishiwaki Yuji
    Department of Environmental and Occupational Health, School of Medicine, Toho University

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タイトル別名
  • Prevalence and Risk Factors of Nasopharyngeal Carriage of <i>Streptococcus pneumoniae</i> in Healthy Children in Japan

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The findings of this study revealed a 22% prevalence of Streptococcus pneumoniae among healthy children in Japan; the prevalence tended to increase with age. We identified attendance at day-care facilities and the presence of older siblings as the major risk factors associated with pneumococcal carriage. A significant decrease in pneumococcal colonization was observed among children during the summer; however, a seasonal variation was independent of various factors. Our findings suggest that prior immunization with heptavalent pneumococcal conjugate vaccine within the current recommended schedule is required for children exposed to these risk factors.

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