The First Identification of <i>Rotavirus B</i> from Children and Adults with Acute Diarrhoea in Kathmandu, Nepal

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著者

    • Alam Md. Mahbub
    • Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, and the Global Centre of Excellence, Nagasaki University
    • Pun Sher B.
    • Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, and the Global Centre of Excellence, Nagasaki University|Sukraraj Tropical and Infectious Disease Hospital
    • Gauchan Punita
    • Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, and the Global Centre of Excellence, Nagasaki University
    • Yokoo Michiyo
    • Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, and the Global Centre of Excellence, Nagasaki University
    • Doan Yen Hai
    • Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, and the Global Centre of Excellence, Nagasaki University
    • Tran T. N. Hoa
    • Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, and the Global Centre of Excellence, Nagasaki University
    • Nakagomi Toyoko
    • Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, and the Global Centre of Excellence, Nagasaki University
    • Nakagomi Osamu
    • Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, and the Global Centre of Excellence, Nagasaki University

抄録

<i>Rotavirus B</i> (RVB) in the genus <i>Rotavirus</i> of the family <i>Reoviridae</i> is known to be a cause of acute gastroenteritis among children and adults in parts of Asia including China, India, Bangladesh and Myanmar. In a 15-month surveillance programme between March 2007 and May 2008, 3,080 stool specimens were collected from children and adults with acute gastroenteritis in an infectious disease hospital in Kathmandu, Nepal. In 25 (0.8%) specimens RVB was detected, for the first time in Nepal, by the use of polyacrylamide gel electrophoresis followed by confirmation with reverse-transcription PCR and sequencing. The strains detected in this study had very similar electropherotypes, and their VP7 sequences were almost identical and phylogenetically belonged to the Indo-Bangladeshi lineage which was distinct from the Chinese lineage. Thus, this study showed the circulation of RVB strains belonging to the Indo-Bangladeshi lineage in a broader region than previously documented, suggesting that this phylogenetic divide corresponded to the geographic divide created by the Himalayan Mountains. Further studies may be warranted to identify and characterize the RVB strains in northern Vietnam which is adjacent to southern China with a long and less mountainous border.

収録刊行物

  • 熱帯医学会報

    熱帯医学会報 41(3), 129-134, 2013

    日本熱帯医学会

各種コード

  • NII論文ID(NAID)
    130003383631
  • 本文言語コード
    ENG
  • ISSN
    1348-8945
  • データ提供元
    J-STAGE 
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